@article{14,
  author = {Kai-Hua Jia and Hui Liu and Ren-Gang Zhang and Jie Xu and Shan-Shan Zhou and Si-Qian Jiao and Xue-Mei Yan and Xue-Chan Tian and Tian- Le Shi and Hang Luo and Zhi-Chao Li and Yu-Tao Bao and Shuai Nie and Jing-Fang Guo and Ilga Porth and Yousry El-Kassaby and Xiao-Ru Wang and Charles Chen and Yves Van de Peer and Wei Zhao and Jian-Feng Mao},
  title = {Chromosome-scale assembly and evolution of the tetraploid Salvia splendens (Lamiaceae) genome.},
  abstract = {<p>Polyploidization plays a key role in plant evolution, but the forces driving the fate of homoeologs in polyploid genomes, i.e., paralogs resulting from a whole-genome duplication (WGD) event, remain to be elucidated. Here, we present a chromosome-scale genome assembly of tetraploid scarlet sage (Salvia splendens), one of the most diverse ornamental plants. We found evidence for three WGD events following an older WGD event shared by most eudicots (the γ event). A comprehensive, spatiotemporal, genome-wide analysis of homoeologs from the most recent WGD unveiled expression asymmetries, which could be associated with genomic rearrangements, transposable element proximity discrepancies, coding sequence variation, selection pressure, and transcription factor binding site differences. The observed differences between homoeologs may reflect the first step toward sub- and/or neofunctionalization. This assembly provides a powerful tool for understanding WGD and gene and genome evolution and is useful in developing functional genomics and genetic engineering strategies for scarlet sage and other Lamiaceae species.</p>
},
  year = {2021},
  journal = {Horticulture research},
  volume = {8},
  pages = {177},
  month = {09/2021},
  issn = {2662-6810},
  doi = {10.1038/s41438-021-00614-y},
  language = {eng},
}